Human NCF1/NOXO2/SH3PXD1A recombinant protein

Cat.#: 518715

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Product Information

  • Product Name
    Human NCF1/NOXO2/SH3PXD1A recombinant protein
  • Documents
  • Description
    Neutrophil cytosol factor 1( NCF1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is characterized as a multicomponent enzyme which is activated to produce superoxide anion. NCF2, NCF1, and a membrane bound cytochrome b558 are required for the activation of the latent NADPH oxidase. The human NCF1 gene encodes a 390 amino acids protein without a signal peptide. The NCF1 gene interacts with other subunits of nicotinamide adenine dinucleotide phosphate-oxidase (NADPH) and plays an important role in innate immunity, producing reactive oxygen species and reducing the severity and duration of parasitic infection and autoimmune disease. NCF1 also has a role in T cell activation.
  • Protein name
    neutrophil cytosolic factor 1(NCF1)
  • Protein short names
    NOXO2; SH3PXD1A
  • Uniprot ID
    P14598
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human NCF1/NOXO2/SH3PXD1A Met1-Val390 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human NCF1/NOXO2/SH3PXD1A recombinant protein

    Human NCF1/NOXO2/SH3PXD1A recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"