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Product Name
Human NCF1/NOXO2/SH3PXD1A recombinant protein
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Description
Neutrophil cytosol factor 1( NCF1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is characterized as a multicomponent enzyme which is activated to produce superoxide anion. NCF2, NCF1, and a membrane bound cytochrome b558 are required for the activation of the latent NADPH oxidase. The human NCF1 gene encodes a 390 amino acids protein without a signal peptide. The NCF1 gene interacts with other subunits of nicotinamide adenine dinucleotide phosphate-oxidase (NADPH) and plays an important role in innate immunity, producing reactive oxygen species and reducing the severity and duration of parasitic infection and autoimmune disease. NCF1 also has a role in T cell activation.
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Protein name
neutrophil cytosolic factor 1(NCF1)
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Protein short names
NOXO2; SH3PXD1A
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Uniprot ID
P14598
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human NCF1/NOXO2/SH3PXD1A Met1-Val390 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human NCF1/NOXO2/SH3PXD1A recombinant protein
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