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Product Name
Human NCALD (His tag) recombinant protein
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Description
Neurocalcin-delta (NCALD) is a neuronal calcium-binding protein that belongs to the neuronal calcium sensor (NCS) family. It expressed in mammalian brains. NCALD contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein possesses a Ca2+ /myristoyl switch. It is cytosolic at resting calcium levels. However, elevated intracellular calcium levels induce a conformational change which exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. NCALD protein is thought to be a regulator of G protein-coupled receptor signal transduction.
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Protein name
neurocalcin delta(NCALD)
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Uniprot ID
P61601
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human NCALD Met1-Phe193 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human NCALD (His tag) recombinant protein
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