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Product Name
Human MYOC/GLC1A/TIGR (His tag) recombinant protein
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Description
Myocilin is a variably glycosylated 65kD secreted polypeptide. Myocilin is a member of Olfactomedin-related protein family. Myocilin is expressed in large amounts in various types of muscle, ciliary body, papillary sphincter, skeletal muscle, heart and other tissues. Myocilin is predominantly expressed in the retina. In normal eyes, it is found in the inner uveal meshwork region and the anterior portion of the meshwork. In contrast, in many glaucomatous eyes, it is found in more regions of the meshwork and appeared more intensively than in normal eyes, regardless of the type or clinical severity of glaucoma. Myocilin may participate in the obstruction of fluid outflow in the trabecular meshwork.
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Protein name
myocilin(MYOC)
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Protein short names
GLC1A; TIGR
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Uniprot ID
Q99972
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human MYOC/GLC1A/TIGR Ile227-Met504 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human MYOC/GLC1A/TIGR (His tag) recombinant protein
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