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Product Name
Human MSX2 Recombinant protein (GST tag)
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Description
Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antogonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter. {PubMed:12145306}.
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Protein name
Homeobox protein MSX-2
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Protein short names
HOX8
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Uniprot ID
P35548
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Gene Name
MSX2; HOX8
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human MSX2 (NP_002440.2) 50-120 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human MSX2 SDS-PAGE
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