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Product Name
Human MOF Recombinant protein (His tag)
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Description
Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex. Can also acetylate TP53/p53 at 'Lys-120'. {PubMed:12397079, PubMed:15923642, PubMed:20018852, PubMed:21217699, PubMed:22020126, PubMed:22547026}.
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Protein name
Histone acetyltransferase KAT8
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Protein short names
MOF; MYST1
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Uniprot ID
Q9H7Z6
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Gene Name
KAT8; MOF; MYST1; PP7073
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human KAT8 (NP_892003.2) 118-467 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human MOF SDS-PAGE
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