Human MAPT/MAPTL/MTBT1/TAU recombinant protein

Cat.#: 519494

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Product Information

  • Product Name
    Human MAPT/MAPTL/MTBT1/TAU recombinant protein
  • Documents
  • Description
    Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. The tau proteins are the product of alternative splicing from a single gene that in humans is designated MAPT. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
  • Protein name
    microtubule associated protein tau(MAPT)
  • Protein short names
    MAPTL; MTBT1; TAU
  • Uniprot ID
    P10636-8
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human MAPT/MAPTL/MTBT1/TAU Met1-Leu441 is expressed.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human MAPT/MAPTL/MTBT1/TAU recombinant protein

    Human MAPT/MAPTL/MTBT1/TAU recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"