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Product Name
Human LSM1/CASM (His tag) recombinant protein
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Description
U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) belongs to the snRNP Sm proteins family. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which plays an important role in pre-mRNA splicing. LSM1 binds specifically to the 3-terminal U-tract of U6snRNA. LSM1 can interact with SLBP when histone mRNA is being rapidly degraded during the S phase. In addition, LSM1 is associated with cellular transformation and the progression of several malignancies including mesothelioma, lung cancer and breast cancer.
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Protein name
LSM1 homolog, mRNA degradation associated(LSM1)
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Protein short names
CASM
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Uniprot ID
O15116
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human LSM1/CASM Met1-Tyr133 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human LSM1/CASM (His tag) recombinant protein
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