Human LPCAT2 Recombinant protein (GST tag)

Cat.#: 509602

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Product Information

  • Product Name
    Human LPCAT2 Recombinant protein (GST tag)
  • Documents
  • Description
    Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. Also catalyzes the conversion of 1-acyl-sn-glycero-3-phosphocholine to 1,2-diacyl-sn-glycero-3-phosphocholine. {PubMed:20363836, PubMed:21498505}.
  • Protein name
    Lysophosphatidylcholine acyltransferase 2
  • Protein short names
    AGPAT11; AYTL1
  • Uniprot ID
    Q7L5N7
  • Gene Name
    LPCAT2; AGPAT11; AYTL1
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human LPCAT2 (NP_060309.2) 161-544 aa was fused with the N-terminal GST tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human LPCAT2 SDS-PAGE

    Recombinant human LPCAT2 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"