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  • Human LCN2/HNL/NGAL (His tag) recombinant protein

Human LCN2/HNL/NGAL (His tag) recombinant protein

Cat.#: 518070

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Product Information

  • Product Name
    Human LCN2/HNL/NGAL (His tag) recombinant protein
  • Documents
  • Description
    LCN2 is iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. LCN2 binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. LCN2 is involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. LCN2 is involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth.
  • Protein name
    lipocalin 2(LCN2)
  • Protein short names
    HNL; NGAL
  • Uniprot ID
    P80188
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human LCN2/HNL/NGAL Gln21-Gly198 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human LCN2/HNL/NGAL (His tag) recombinant protein

    Human LCN2/HNL/NGAL (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"