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Human LARP1 Recombinant protein (GST tag)

Cat.#: 509449

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Special Price 294.7 USD

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Product Information

  • Product Name
    Human LARP1 Recombinant protein (GST tag)
  • Documents
  • Description
    RNA-binding protein that promotes translation of specific classes of mRNAs downstream of the mTORC1 complex. Associates with the mRNA 5'cap in an MTOR-dependent manner and associates with mRNAs containing a 5' terminal oligopyrimidine (5'TOP) motif, which is present in mRNAs encoding for ribosomal proteins and several components of the translation machinery. Associates with actively translating ribosomes via interaction with PABPC1/PABP and stimulates translation of mRNAs containing a 5'TOP, thereby regulating cell growth and proliferation. {PubMed:20430826, PubMed:23711370, PubMed:24532714}.
  • Protein name
    La-related protein 1
  • Protein short names
    KIAA0731; LARP
  • Uniprot ID
    Q6PKG0
  • Gene Name
    LARP1; KIAA0731; LARP
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human LARP1 (NP_291029.2) 814-1096 aa was fused with the N-terminal GST tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human LARP1(Full length) SDS-PAGE

    Recombinant human LARP1(Full length) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"