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Product Name
Human KIAA0430 Recombinant protein (His tag)
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Description
Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks (By similarity).
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Protein name
Meiosis arrest female protein 1
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Protein short names
LKAP; MARF1
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Uniprot ID
Q9Y4F3
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Gene Name
KIAA0430; LKAP; MARF1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human KIAA0430 (XP_054185119.1) 1-286 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human KIAA0430 SDS-PAGE
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