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Product Name
Human KCNIP4 Recombinant protein (His tag)
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Description
Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner (PubMed:11847232, PubMed:18957440, PubMed:23576435). Modulates KCND3/Kv4.3 currents (PubMed:23576435). Isoform 4 does not increase KCND2 expression at the cell membrane (PubMed:18957440). Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane. {UniProtKB:Q6PHZ8, PubMed:11847232, PubMed:18957440, PubMed:23576435}.
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Protein name
Kv channel-interacting protein 4
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Protein short names
CALP; KCHIP4
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Uniprot ID
Q6PIL6
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Gene Name
KCNIP4; CALP; KCHIP4
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human KCNIP4 (NP_079497.2) 1-250 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human KCNIP4 SDS-PAGE
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