Human INO80 Recombinant protein (GST tag)

Cat.#: 509067

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Product Information

  • Product Name
    Human INO80 Recombinant protein (GST tag)
  • Documents
  • Description
    DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double-stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle. {PubMed:16230350, PubMed:16298340, PubMed:17721549, PubMed:20237820, PubMed:20687897, PubMed:20855601, PubMed:21303910}.
  • Protein name
    DNA helicase INO80
  • Protein short names
    INO80A; INOC1; KIAA1259
  • Uniprot ID
    Q9ULG1
  • Gene Name
    INO80; INO80A; INOC1; KIAA1259
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human INO80 (XP_054234202.1) 1217-1556 aa was fused with the N-terminal GST tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human INO80 SDS-PAGE

    Recombinant human INO80 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"