Human ING3 Recombinant protein (GST tag)

Cat.#: 509035

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Product Information

  • Product Name
    Human ING3 Recombinant protein (GST tag)
  • Documents
  • Description
    Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome. {PubMed:12545155, PubMed:14966270, PubMed:24463511}.
  • Protein name
    Inhibitor of growth protein 3
  • Uniprot ID
    Q9NXR8
  • Gene Name
    ING3; HSPC301
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human ING3 (NP_061944.2) 1-89 aa was fused with the N-terminal GST tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human ING3 SDS-PAGE

    Recombinant human ING3 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"