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Product Name
Human IMPDH2/IMPD2 (His tag) recombinant protein
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Description
IMPDH2 is a cytosolic enzyme which belongs to the IMPDH/GMPR family. IMPDH2 catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'- monophosphate. IMPDH2 is consequently involved in maintaining cellular guanine deoxy- and ribonucleotide pools required for DNA and RNA synthesis. In addition, IMPDH1 and IMPDH2 are targets for the important immunosuppressive drug, mycophenolic acid (MPA).
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Protein name
inosine monophosphate dehydrogenase 2(IMPDH2)
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Protein short names
IMPD2
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Uniprot ID
P12268
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human IMPDH2/IMPD2 Met1-Phe514 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human IMPDH2/IMPD2 (His tag) recombinant protein
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