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Product Name
Human IMPDH1 Recombinant protein (His tag)
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Description
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
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Protein name
Inosine-5'-monophosphate dehydrogenase 1
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Protein short names
IMPD1
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Uniprot ID
P20839
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Gene Name
IMPDH1; IMPD1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
170-235 aa encoded by NM_183243 was inserted into PET28a vector
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human IMPDH1 SDS-PAGE
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