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Product Name
Human IL33/C9orf26/IL1F11/NFHEV (His tag) recombinant protein
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Description
Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.
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Protein name
interleukin 33(IL33)
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Protein short names
C9orf26; IL1F11; NFHEV
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Uniprot ID
O95760
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human IL33/C9orf26/IL1F11/NFHEV Ser112-Thr270 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human IL33/C9orf26/IL1F11/NFHEV (His tag) recombinant protein
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