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Product Name
Human ID1 Recombinant protein (GST tag)
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Description
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer (By similarity).
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Protein name
DNA-binding protein inhibitor ID-1
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Protein short names
BHLHB24; ID
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Uniprot ID
P41134
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Gene Name
ID1; BHLHB24; ID
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
1-67 aa encoded by NM_002165 was inserted into PGEX-4T vector
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human ID1 SDS-PAGE
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