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Product Name
Human ICOSLG/B7H2/B7RP1/ICOSL/KIAA0653 (His tag) recombinant protein
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Description
Inducible Co-Stimulator Ligand (ICOSLG) belongs to the immunoglobulin superfamily. ICOSLG contains Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. ICOSLG acts as a costimulatory signal for T-cell proliferation and cytokine secretion, it also induces B-cell proliferation and differentiation into plasma cells. It could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. ICOSLG is widely expressed lymph nodes, leukocytes and spleen, detected on activated monocytes and dendritic cells.
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Protein name
ICOS ligand(LOC102723996)
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Protein short names
B7H2; B7RP1; ICOSL; KIAA0653
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Uniprot ID
O75144
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human ICOSLG/B7H2/B7RP1/ICOSL/KIAA0653 Asp19-Ser258 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human ICOSLG/B7H2/B7RP1/ICOSL/KIAA0653 (His tag) recombinant protein
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