Human HPD/PPD (His tag) recombinant protein

Cat.#: 518789

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Product Information

  • Product Name
    Human HPD/PPD (His tag) recombinant protein
  • Documents
  • Description
    4-Hydroxyphenylpyruvate Dioxygenase (4HPPD) belongs to the 4HPPD family. 4HPPD is a key enzyme in the degradation of tyrosine, which catalyzes the second reaction in the catabolism of tyrosine the conversation of 4-hydroxyphenylpyruvate to homogentisate. 4HPPD exists in homodimer forms, which uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. When the active 4HPPD enzyme concentration is low in the human body, it results in high levels of tyrosine concentration in the blood, which can cause mild mental retardation at birth, and degradation in vision as a patient grows older.
  • Protein name
    4-hydroxyphenylpyruvate dioxygenase(HPD)
  • Protein short names
    PPD
  • Uniprot ID
    P32754
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human HPD/PPD Met1-Met393 is expressed with a 6His tag at the N-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human HPD/PPD (His tag) recombinant protein

    Human HPD/PPD (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"