Human HOPX Recombinant protein (GST tag)

Cat.#: 508746

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Product Information

  • Product Name
    Human HOPX Recombinant protein (GST tag)
  • Documents
  • Description
    Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor.
  • Protein name
    Homeodomain-only protein
  • Protein short names
    HOD; HOP; LAGY; NECC1; OB1
  • Uniprot ID
    Q9BPY8
  • Gene Name
    HOPX; HOD; HOP; LAGY; NECC1; OB1
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human HOPX (XP_054207067.1) 39-111 aa was fused with the N-terminal GST tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human HOPX SDS-PAGE

    Recombinant human HOPX SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"