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Product Name
Human HES6 Recombinant protein (His tag)
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Description
Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation (By similarity).
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Protein name
Transcription cofactor HES-6
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Protein short names
BHLHB41
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Uniprot ID
Q96HZ4
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Gene Name
HES6; BHLHB41
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human HES6 (NP_061115.2) 1-224 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human HES6 SDS-PAGE
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