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Product Name
Human GPNMB/HGFIN/NMB/UNQ1725/PRO9925 (His tag) recombinant protein
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Description
Osteoactivin is an intracellular glycoprotein belongs to the NMB/pMEL-17 family, which is asscociated with cell endosomal/lysomal compartments. Human Osteoactivin is a 560 amino acid type I transmembrane protein, and one alternate splice form shows a 12 amino acid insert between amino acid 339-340. An additional 206 amino acid isoform shows a mutation at position 181 that results in a 26 amino acid substitution for the C-terminal 380 amino acids. Cells knowns to express Osteoactivin include fibroblast, osteoblasts, myeloid dendritic cell, melanocytes, plus fetal chondrocytes and stratum basale keratinocytes, macrophages/keratinocytes.
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Protein name
glycoprotein nmb(GPNMB)
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Protein short names
HGFIN; NMB; UNQ1725; PRO9925
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Uniprot ID
Q14956
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human GPNMB/HGFIN/NMB/UNQ1725/PRO9925 Ala22-Pro486 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human GPNMB/HGFIN/NMB/UNQ1725/PRO9925 (His tag) recombinant protein
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