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Product Name
Human GNE Recombinant protein (GST tag)
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Description
Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development (By similarity). Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. {, PubMed:10334995}.
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Protein name
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
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Protein short names
GLCNE
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Uniprot ID
Q9Y223
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Gene Name
GNE; GLCNE
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human GNE (NP_001121699.1) 407-753 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human GNE SDS-PAGE
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