Cart 2
  • Human GFER/ALR/HERV1/HPO (His tag) recombinant protein

Human GFER/ALR/HERV1/HPO (His tag) recombinant protein

Cat.#: 518006

Special Price 261.2 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Human GFER/ALR/HERV1/HPO (His tag) recombinant protein
  • Documents
  • Description
    GFER is a hepatotrophic growth factor and flavin-linked sulfhydryl oxidase which belongs to the Erv1/ALR family of proteins. GFER is widely expressed in various human tissues. They are two isoforms of this protein. Isoform 1 could regenerate the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. Isoform 2 may act as an autocrine hepatotrophic growth factor promoting liver regeneration. GFER could also induce the expression of S-adenosylmethionine decarboxyl-ase and ornithine decarboxylases (ODC). S-adenosylmethionine decarboxyl-ase and ornithine decarboxylases play an important role in the synthesis of polyamines.
  • Protein name
    growth factor, augmenter of liver regeneration(GFER)
  • Protein short names
    ALR; HERV1; HPO
  • Uniprot ID
    P55789
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human GFER/ALR/HERV1/HPO Met1-Asp125 is expressed with a 6His tag at the N-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human GFER/ALR/HERV1/HPO (His tag) recombinant protein

    Human GFER/ALR/HERV1/HPO (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"