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Product Name
Human FTH1/FTH/FTHL6/OK/SW-cl.84/PIG15 (His tag) recombinant protein
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Description
Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Ferritin is composed of 24 subunits of the light and heavy ferritin chains. It plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney. Variation of ferritin subunit composition may affect iron absorption and release in different tissues. Deficiency of ferritin proteins may cause several neurodegenerative diseases. Almost all living organisms can produce this protein, including algae, bacteria, higher plants, and animals.
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Protein name
ferritin heavy chain 1(FTH1)
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Protein short names
FTH; FTHL6; OK; SW-cl.84; PIG15
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Uniprot ID
P02794
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human FTH1/FTH/FTHL6/OK/SW-cl.84/PIG15 Met1-Ser183 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human FTH1/FTH/FTHL6/OK/SW-cl.84/PIG15 (His tag) recombinant protein
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