Anti-Ferritin Heavy Chain Rabbit antibody

Cat.#: 166949

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Product Information

  • Product Name
    Anti-Ferritin Heavy Chain Rabbit antibody
  • Documents
  • Description
    Ferritin Heavy Chain Rabbit polyclonal antibody
  • Tested applications
    WB, ICC/IF
  • Species reactivity
    Human, Mouse, Rat
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthesized peptide derived from human Ferritin
  • Clonality
    Polyclonal
  • Formulation
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/500-1/2000

    ICC/IF: 1/50-1/200

  • Validations

    Western blot analysis of Ferritin expression in Jurkat cell lysate.

    Western blot analysis of Ferritin expression in Jurkat cell lysate.

    Immunofluorescent analysis of Jurkat cells, using Ferritin Antibody.

    Immunofluorescent analysis of Jurkat cells, using Ferritin Antibody.

  • Background
    Swiss-Prot Acc.P02794.The assembled ferritin molecule, often referred to as a nanocage, can store up to 4,500 atoms of iron. It forms a holoenzyme of ~450 kDa, consisting of 24 subunits made up of two types of polypeptide chains: ferritin heavy chain and ferritin light chain, each having unique functions. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe(II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe(III).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"