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Product Name
Human FPR2 Recombinant protein (His tag)
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Description
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
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Protein name
N-formyl peptide receptor 2
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Protein short names
FPRH1; FPRL1; LXA4R
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Uniprot ID
P25090
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Gene Name
FPR2; FPRH1; FPRL1; LXA4R
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human FPR2 (NP_001005738.1) 1-351 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human FPR2 SDS-PAGE
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