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Product Name
Human FH recombinant protein
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Description
Fumarase is an enzyme that catalyze the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid or Krebs cycle. Fumarase exists in both form, cytosolic formand N-terminal extend mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase is thought to act as a tumor suppressor, which deficiency can lead to progressive encephalopathy, cerebral atrophy and development delay.
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Protein name
fumarate hydratase(FH)
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Uniprot ID
P07954
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human FH Ala45-Lys510 is expressed.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human FH recombinant protein
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