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Product Name
Human FCRL1/FCRH1/IFGP1/IRTA5 (His tag) recombinant protein
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Description
Fc Receptor-Like Protein 1 (FCRL1) is a single-pass type I membrane protein that may function as an activating coreceptor in B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It can be detected in the spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. It is specifically expressed by mature B lineage cells with higher expression at the protein level in naive B cells compared to memory B cells. FCRL1 contains three extracellular C2-like immunoglobulin domains, a transmembrane domain, and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs and may play a role in the regulation of cancer cell growth.
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Protein name
Fc receptor like 1(FCRL1)
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Protein short names
FCRH1; IFGP1; IRTA5
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Uniprot ID
Q96LA6
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human FCRL1/FCRH1/IFGP1/IRTA5 Ala17-Asn303 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human FCRL1/FCRH1/IFGP1/IRTA5 (His tag) recombinant protein
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