Anti-FCRL1/FCRH1 antibody

Anti-FCRL1/FCRH1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit polyclonal to FCRL1/FCRH1

ELISA, WB, IP

Mouse FCRL1 / FCRH1

FCRH1 antibody; IFGP1 antibody; IRTA5 antibody; CD307a antibody; Bxmh1 antibody; Fcrh1 antibody; Ifgp1 antibody; Bxmas1 antibody; Bxmh1b antibody; Fcrh1l antibody; Fcrh1s antibody; A230020G22Rik antibody; DKFZp667O1421 antibody; Fcrh1 antibody; FCRH1 antibody; Fcrh1l antibody; Fcrh1s antibody; Fcrl1 antibody; FCRL1 antibody; Ifgp1 antibody; IRTA5 antibody; A230020G22Rik antibody; Bxmas1 antibody; Bxmh1 antibody; Bxmh1b antibody; IFGP1 antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Mouse FCRL1 / FCRH1 (rh FCRL1 / FCRH1; Q8R4Y0-2; Met1-Thr204). FCRL1 / FCRH1 specific IgG was purified by Mouse FCRL1 / FCRH1 affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I  membrane protein which contains three Ig-like C2-type (immunoglobulin-like) domains. It is a cell-surface membrane protein belonging to FCRL family and is preferentially expressed on B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It is detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. FCRL1 is specifically expressed by mature B lineage cells with higher expression in naive versus memory B cells (at protein level). Human Fc receptor-like molecules (FCRL1, FCRL2, FCRL3, FCRL4, FCRL5) have tyrosine-based immunoregulatory potential and are expressed by B-lineage subpopulations. FCRL1 may function as an activating coreceptor in B cells. It may also function in B cells activation and differentiation.

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• Baranov K. et al., 2008, J Immunol Methods. 332 (1-2): 73-81.