-
Product Name
Human FBXL12 Recombinant protein (His tag)
- Documents
-
Description
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the polyubiquitination and proteasomal degradation of CAMK1 leading to disruption of cyclin D1/CDK4 complex assembly which results in G1 cell cycle arrest in lung epithelia. {PubMed:23707388}.
-
Protein name
F-box/LRR-repeat protein 12
-
Protein short names
FBL12
-
Uniprot ID
Q9NXK8
-
Gene Name
FBXL12; FBL12
-
Source/Expression Host
E. coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the human FBXL12 (XP_054177302.1) 187-343 aa was fused with the polyhistidine tag
-
Protein Species
Human
-
Activity
Not tested.
-
Validations
Recombinant human FBXL12 SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"