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Product Name
Human FANCL Recombinant protein (His tag)
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Description
Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth. {PubMed:12973351, PubMed:16916645, PubMed:17938197, PubMed:19111657, PubMed:19589784}.
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Protein name
E3 ubiquitin-protein ligase FANCL
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Protein short names
PHF9
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Uniprot ID
Q9NW38
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Gene Name
FANCL; PHF9
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human FANCL (NP_060532.2) 1-375 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human FANCL(Full length) SDS-PAGE
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