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Product Name
Human EIF4EBP3 Recombinant protein (GST tag)
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Description
Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. {UniProtKB:Q13541}.
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Protein name
Eukaryotic translation initiation factor 4E-binding protein 3
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Uniprot ID
O60516
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Gene Name
EIF4EBP3
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
46-90 aa encoded by NM_003732 was inserted into PGEX-4T vector
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human EIF4EBP3 SDS-PAGE
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