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Product Name
Human E4F1 Recombinant protein (His tag)
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Description
May function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin-associated TP53. Functions in cell survival and proliferation through control of the cell cycle. Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription.; Identified as a cellular target of the adenoviral oncoprotein E1A, it is required for both transcriptional activation and repression of viral genes.
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Protein name
Transcription factor E4F1
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Protein short names
E4F
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Uniprot ID
Q66K89
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Gene Name
E4F1; E4F
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human E4F1 (XP_054235707.1) 489-837 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human E4F1 SDS-PAGE
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