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Human DNMT3L Recombinant protein (His tag)

Cat.#: 507287

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Special Price 294.7 USD

Availability: 2-3 weeks
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Product Information

  • Product Name
    Human DNMT3L Recombinant protein (His tag)
  • Documents
  • Description
    Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3. {PubMed:17687327}.
  • Protein name
    DNA
  • Uniprot ID
    Q9UJW3
  • Gene Name
    DNMT3L
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human DNMT3L (NP_787063.1) 1-386 aa was fused with the polyhistidine tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human DNMT3L SDS-PAGE

    Recombinant human DNMT3L SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"