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Human DIO3 Recombinant protein (His tag)

Cat.#: 507221

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Special Price 294.7 USD

Availability: 2-3 weeks
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Product Information

  • Product Name
    Human DIO3 Recombinant protein (His tag)
  • Documents
  • Description
    Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development. {PubMed:7593630}.
  • Protein name
    Thyroxine 5-deiodinase
  • Protein short names
    ITDI3; TXDI3
  • Uniprot ID
    P55073
  • Gene Name
    DIO3; ITDI3; TXDI3
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    192-278 aa encoded by BC017717 was inserted into PET30a vector
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human DIO3 SDS-PAGE

    Recombinant human DIO3 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"