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Product Name
Human DHFR Recombinant protein (His tag)
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Description
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFRL1. {PubMed:12096917, PubMed:21876188}.
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Protein name
Dihydrofolate reductase
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Uniprot ID
B0YJ76
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Gene Name
DHFR
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human DHFR (NP_000782.1) 1-187 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human DHFR SDS-PAGE
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