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Product Name
Human DEFB1/BD1/HBD1 recombinant protein
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Description
β-Defensin 1 (DEFB1) is a member of the β-defensin family, which is highly expressed by epithelial cells. β-defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. β-defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in β-Defensin-1 contribute to asthma diagnosis, with apparent gender-specific effects in human. β-defensin 1 may also play a role in the pathogenesis of severe sepsis. In addition, β-defensin 1 is associated with induction profiles in gingival keratinocytes.
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Protein name
defensin beta 1(DEFB1)
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Protein short names
BD1; HBD1
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Uniprot ID
P60022
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human DEFB1/BD1/HBD1 Gly22-Lys68 is expressed.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human DEFB1/BD1/HBD1 recombinant protein
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