Human DEFB1/BD1/HBD1 recombinant protein

Cat.#: 519615

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Product Information

  • Product Name
    Human DEFB1/BD1/HBD1 recombinant protein
  • Documents
  • Description
    β-Defensin 1 (DEFB1) is a member of the β-defensin family, which is highly expressed by epithelial cells. β-defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. β-defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in β-Defensin-1 contribute to asthma diagnosis, with apparent gender-specific effects in human. β-defensin 1 may also play a role in the pathogenesis of severe sepsis. In addition, β-defensin 1 is associated with induction profiles in gingival keratinocytes.
  • Protein name
    defensin beta 1(DEFB1)
  • Protein short names
    BD1; HBD1
  • Uniprot ID
    P60022
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human DEFB1/BD1/HBD1 Gly22-Lys68 is expressed.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human DEFB1/BD1/HBD1 recombinant protein

    Human DEFB1/BD1/HBD1 recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"