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Product Name
Human DCUN1D1/DCUN1L1/RP42/SCCRO (His tag) recombinant protein
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Description
DCN1-Like Protein 1 is a protein containing 1 DCUN1 domain and 1 UBA-like domain. DCN1-Like Protein 1 contains part of an E3 Ubiquitin Ligase Complex for Neddylation. It is required for Neddylation of Cullin components of E3 Cullin-RING Ubiquitin Ligase complexes. It enhances the rate of Cullins Neddylation. DCN1-Like Protein 1 recruits the NEDD8-charged E2 Enzyme to the Cullin component. DCUN1D1 is involved in the release of inhibitory effects of CAND1 on the Cullin-RING Ligase E3 complex assembly and activity. It acts also as an oncogene facilitating malignant transformation and carcinogenic progression.
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Protein name
defective in cullin neddylation 1 domain containing 1(DCUN1D1)
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Protein short names
DCUN1L1; RP42; SCCRO
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Uniprot ID
Q96GG9
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human DCUN1D1/DCUN1L1/RP42/SCCRO Met1-Val259 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human DCUN1D1/DCUN1L1/RP42/SCCRO (His tag) recombinant protein
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