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Product Name
Human CYP24A1 Recombinant protein (His tag)
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Description
Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.
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Protein name
1,25-dihydroxyvitamin D(3 24-hydroxylase, mitochondrial
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Protein short names
CYP24
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Uniprot ID
Q07973
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Gene Name
CYP24A1; CYP24
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human CYP24A1 (NP_001411270.1) 1-350 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human CYP24A1 SDS-PAGE
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