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Product Name
Human CRNN/C1orf10/DRC1/PDRC1/SEP53 (His tag) recombinant protein
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Description
Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. Cornulin involves in the mucosal/epithelial immune response and epidermal differentiation. Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When Cornulin is overexpressed in oral squamous carcinoma cell lines, it regulates negatively cell proliferation by the induction of G1 arrest.
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Protein name
cornulin(CRNN)
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Protein short names
C1orf10; DRC1; PDRC1; SEP53
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Uniprot ID
Q9UBG3
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CRNN/C1orf10/DRC1/PDRC1/SEP53 Met1-Ser140 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CRNN/C1orf10/DRC1/PDRC1/SEP53 (His tag) recombinant protein
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