-
Product Name
Human CRNN/C1orf10/DRC1/PDRC1/SEP53 (His tag) recombinant protein
- Documents
-
Description
Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. Cornulin involves in the mucosal/epithelial immune response and epidermal differentiation. Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When Cornulin is overexpressed in oral squamous carcinoma cell lines, it regulates negatively cell proliferation by the induction of G1 arrest.
-
Protein name
cornulin(CRNN)
-
Protein short names
C1orf10; DRC1; PDRC1; SEP53
-
Uniprot ID
Q9UBG3
-
Source/Expression Host
E.coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the Human CRNN/C1orf10/DRC1/PDRC1/SEP53 Met1-Ser140 is expressed with a 6His tag at the N-terminus.
-
Protein Species
Human
-
Purity
>95% as determined by SDS-PAGE.
-
Validations
Human CRNN/C1orf10/DRC1/PDRC1/SEP53 (His tag) recombinant protein
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"