Human COQ7 (His tag) recombinant protein

Human COQ7 (His tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Ubiquinone Biosynthesis Protein COQ7 Homolog (COQ7) is a mitochondrion inner membrane and peripheral membrane protein which belongs to the COQ7 family. It is expressed dominantly in heart and skeletal muscle. COQ7 is synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. COQ7 is involved in lifespan determination in ubiquinone-independent manner and also involved in ubiquinone biosynthesis. COQ7 is potential central metabolic regulator. Human COQ7 protein contains 179 amino acids, is mostly helical, and contains an alpha-helical membrane insertion. It has been shown that mutations in the gene are associated with increased life span. Defects of the gene slow down a variety of developmental and physiological processes, including the cell cycle, embryogenesis, post-embryonic growth, rhythmic behaviors and aging.

coenzyme Q7, hydroxylase(COQ7)

Q99807

Human Cells

A DNA sequence encoding the Human COQ7 Ser37-Leu217 is expressed with a 6His tag at the C-terminus.

Human

>95% as determined by SDS-PAGE.