• Human CNOT2 Recombinant protein (His tag)

Human CNOT2 Recombinant protein (His tag)

Cat.#: 506712

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Product Information

  • Product Name
    Human CNOT2 Recombinant protein (His tag)
  • Documents
  • Description
    Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem (ES) cell identity. {PubMed:14707134, PubMed:16712523, PubMed:21299754, PubMed:22367759}.
  • Protein name
    CCR4-NOT transcription complex subunit 2
  • Protein short names
    CDC36; NOT2
  • Uniprot ID
    Q9NZN8
  • Gene Name
    CNOT2; CDC36; NOT2; HSPC131; MSTP046
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    336-540 aa encoded by XM_011538399 was inserted into PET28a vector
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human CNOT2 SDS-PAGE

    Recombinant human CNOT2 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"