Human CLM-9 / TREM4 (Fc Tag) recombinant protein

Human CLM-9 / TREM4 (Fc Tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

CLM-9, also known as TREM4, is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, microglia, and dendritic cells. CLM-9 may mediate L-selectin-dependent lymphocyte rollings. It binds SELL in a calcium dependent manner. CLM-9 also binds lymphocyte which suggests that it functions in lymphocyte adhesion. The major CLM-9 transcript is expressed highly in human heart, skeletal muscle, and placenta. The mouse protein has been shown to be expressed in capillary endothelial cells. Human CLM-9 mediates the uptake of human IgA2 and mouse IgM.

CMRF35-like molecule 9

D11ERTD736E; TREM-4; TREM4; CLM-9; RP23-398F7.7; CD300 ANTIGEN-LIKE FAMILY MEMBER G; CMRF35-LIKE MOLECULE 9; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 4; 2310016B05RIK; NEPMUCIN; CMRF-35-LIKE MOLECULE-9; CLM9; CD300 MOLECULE LIKE FAMILY MEMBER G; UNQ422/PRO846; CD300 ANTIGEN LIKE FAMILY MEMBER G

Q6UXG3

CD300LG; CLM9; TREM4; UNQ422/PRO846

Human Cells

A DNA sequence encoding the human CD300LG (AAH25395.1) (Met1-Arg247) was expressed, fused with the Fc region of human IgG1 at the C-terminus.

Human

The recombinant human CD300LG/Fc is a disulfide-linked homodimer. The reduced monomer comprises 470 amino acids and has a predicted molecular mass of 51.7 kDa. The apparent molecular mass of the protein is approximately 70 and 34 kDa in SDS-PAGE under reducing conditions.

(74+24.5) % as determined by SDS-PAGE