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Product Name
Human CLM-9 / TREM4 recombinant protein
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Description
CLM-9, also known as TREM4, is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, microglia, and dendritic cells. CLM-9 may mediate L-selectin-dependent lymphocyte rollings. It binds SELL in a calcium dependent manner. CLM-9 also binds lymphocyte which suggests that it functions in lymphocyte adhesion. The major CLM-9 transcript is expressed highly in human heart, skeletal muscle, and placenta. The mouse protein has been shown to be expressed in capillary endothelial cells. Human CLM-9 mediates the uptake of human IgA2 and mouse IgM.
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Protein name
CMRF35-like molecule 9
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Protein short names
CMRF35-LIKE MOLECULE 9; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 4; CLM-9; CD300 ANTIGEN-LIKE FAMILY MEMBER G; RP23-398F7.7; TREM4; D11ERTD736E; TREM-4; CD300 ANTIGEN LIKE FAMILY MEMBER G; CD300 MOLECULE LIKE FAMILY MEMBER G; UNQ422/PRO846; CLM9; NEPMUCIN; 2310016B05RIK; CMRF-35-LIKE MOLECULE-9
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Uniprot ID
Q6UXG3
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Gene Name
CD300LG; CLM9; TREM4; UNQ422/PRO846
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human CD300LG (AAH25395.1)(Met1-Arg247) was expressed with six amino acids (LEVLFQ) at the C-terminus was expressed and purified.
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Protein Species
Human
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Molecular weight
The recombinant human CD300LG consists of 236 amino acids and predicts a molecular mass of 25.5 KDa. It migrates as an approximately 61-66 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human CLM-9 / TREM4 / CD300LG Protein SDS-PAGE
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