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Product Name
Human CLIC2 (His tag) recombinant protein
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Description
Chloride Intracellular Channel Protein 2 (CLIC2) is a critical component of all living cells; it regulatescellular traffic of Chloride ion and it can be inserted into membranes anf form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions, channel activity depends on the pH. CLIC2 is involved in regulating membrane potential and organic solute transport. CLIC2 modulates the activity of RYR2 and inhibits Calcium influx. CLIC2 can be detected in the adult brain, liver, lung, heart, stomach, spleen and testis. It is expressed in fetal liver and adult skeletal muscle. CLIC2 is a potential candidate for one of many diseases linked to Xq28.
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Protein name
chloride intracellular channel 2(CLIC2)
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Uniprot ID
O15247
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CLIC2 Met1-Ser247 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CLIC2 (His tag) recombinant protein
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