-
Product Name
Human CHIA Recombinant protein (His tag)
- Documents
-
Description
Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding. {PubMed:11085997, PubMed:18824549, PubMed:19342690, PubMed:19435888}.
-
Protein name
Acidic mammalian chitinase
-
Uniprot ID
Q9BZP6
-
Gene Name
CHIA
-
Source/Expression Host
E. coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the human CHIA (NP_970615.2) 217-476 aa was fused with the polyhistidine tag
-
Protein Species
Human
-
Activity
Not tested.
-
Validations
Recombinant human CHIA SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"