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Product Name
Human CFD/DF/PFD (His tag) recombinant protein
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Description
Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3, which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the regulation of systemic energy balance and physiologic and pathologic processes, including immunity and inflammation.
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Protein name
complement factor D(CFD)
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Protein short names
DF; PFD
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Uniprot ID
P00746
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CFD/DF/PFD Ile26-Ala253 is expressed with a 10His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CFD/DF/PFD (His tag) recombinant protein
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