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Product Name
Human Adipsin/Complement Factor D (His Tag) recombinant protein
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Description
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
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Protein name
Complement factor D
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Protein short names
COMPLEMENT FACTOR D; PFD; ADN; CFD; DF; ADIPSIN
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Uniprot ID
P00746
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Gene Name
CFD; DF; PFD
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human CFD (P00746) (Ile 26-Ala 253) was fused with a C-terminal polyhistidine tag and a signal peptide at the N-terminus.
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Protein Species
Human
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Molecular weight
The secreted recombinant human CFD consists of 239 amino acids and predicts a molecular mass of 25.8 kDa. As a result of glycosylation, rh CFD migrates as an approximately 33 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 97 % as determined by SDS-PAGE
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Validations
Human Adipsin / Complement Factor D / CFD Protein (His Tag) SDS-PAGE
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